You can always count on Karen for the best advice!

Will returns home from his trip to find Grace and Jack closer than ever.

In Season 4, Jack bumps his head and has a divine experience.

From Patti LuPone to Debbie Reynolds, there's too many musical theatre stars and incredible musical moments to fit into just one video!

Jack (Sean Hayes) tries to seduce Bill (Neil Patrick Harris) at a Welcome Back Home gathering for "ex-gay" people. Karen (Megan Mullally) tags along, hoping to make out with a woman.

Liz (Madonna) and Karen (Megan Mullally) were getting along just fine until a spat over a man in a bar throws their roomie arrangement into a tailspin.

When Will (Eric McCormack) and Grace (Debra Messing) have Vince (Bobby Cannavale) and Nadine (Kristin Davis) over for dinner, hurtful secrets become a bitter digestif.

Grace (Debra Messing) comes with Val (Molly Shannon) to her AA meetings to get free therapy and food, but things get ugly when Karen (Megan Mullally) forces Grace to tell the truth.

When Bobbi, Karen and Jack met for the first time, it was pure magic.

Grace tries a water-filled bra to keep up the appearance of bigger breasts to impress her high school crush.

Jack makes a confession to his mother, and she makes a confession to him.

Watch the best of Will Truman (Eric McCormack) from Will and Grace and subsequently be jealous about how fast he can think on his feet.

During an iconic moment from Season 1, Will asks Grace if he's a bad gay man after returning home from a fight with Jack at the gym.

Jack (Sean Hayes), Karen (Megan Mullally) and Rosario (guest star Shelley Morrison) have an interesting visit with an I.N.S. officer (guest star Peter Paige).

Will, Grace, Jack & Karen all hangout at the White House, for very different reasons.